Inclusion and exclusion criteria
Inclusion criteria :(1) Randomized controlled trials or single-arm trials;
(2) Patients diagnosed with relapsed/refractory DLBCL;
(3) At least one of the efficacy indicators of OS, PFS or ORR was reported;
(4) The treatment are chemotherapy, targeted therapy, and immunotherapy alone or in combination.
Exclusion criteria :
(1) Sample size was less than 10;
(2) Patients with other subtypes, DLBCL transformed from other subtypes, or patients with high-risk disease with undiagnosed relapsed/refractory DLBCL.
Details of
search and inclusion
Literature search : Databases : PubMed , Embase and Cochrane Library
Search deadline : Jan 25, 2021.
Language was limited to English.
The terms used : “relapsed”, “refractory” and “diffuse large B-cell lymphoma” .
Literature inclusion and exclusion:
A total of 854 literatures were identified
624 literatures were screened
106 literatures were assessed for eligibility
58 studies were included in the analysis.
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Detailed search strategies download
PRISMA flow diagram download