Inclusion and exclusion criteria

Inclusion criteria :

(1) Studies were randomized controlled trials;

(2) Subjects were 5 to 12-year-old children with asthma

(3) Treatment drugs were ICS alone;

(4) FEV1 was reported;


Exclusion criteria :

(1) Patients with refractory asthma or other diseases;

(2) Patients undergoing preventive administration or any treatment for acute exacerbation.

(3) Crossover studies that did not report the efficacy of the first cycle.


Details of
search and inclusion

Literature search :

Databases : PubMed, Embase

Search deadline : Mar 2, 2022.

Language was limited to English.

The terms used : “childhood asthma” “Budesonide”, “Ciclesonide”, “Fluticasone furoate”, "Fluticasone propionate" and “Mometasone furoate” .



Literature inclusion and exclusion:

A total of 1758 literatures were identified

1360 literatures were screened

404 literatures were assessed for eligibility

6 studies were included in the analysis.



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Detailed search strategies     download

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